Description

5α-Cholest-8-Ene-3β,6α-Diol CAS NO 570-92-3 is a high-purity steroidal diol derivative, serving as a critical intermediate in advanced organic synthesis and pharmaceutical research. Its unique cholestane-based structure makes it a valuable building block for developing novel bioactive compounds and reference standards. This product is essential for research and development laboratories in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for complex synthetic pathways.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of complex steroid-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or probe in metabolic pathway studies, enzyme inhibition assays, and receptor binding research related to sterol biology.
• Fine Chemical Synthesis: Serves as a versatile chiral building block for the preparation of specialized fine chemicals, catalysts, and ligands in asymmetric synthesis.
• Reference Standard: Employed as a high-purity analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development and validation.
• Academic & Industrial R&D: Facilitates exploratory chemistry in academic institutions and corporate R&D centers for developing new materials and bioactive molecules.

Basic Information

Product Name	5α-Cholest-8-Ene-3β,6α-Diol
CAS No.	570-92-3
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.66 g/mol
Synonyms	5α-Cholest-8-ene-3β,6α-diol; (3β,5α,6α)-Cholest-8-ene-3,6-diol; 3β,6α-Dihydroxy-5α-cholest-8-ene; NSC 163063; 5α-Cholest-8(14)-ene-3β,6α-diol (related isomer); Cholest-8-ene-3,6-diol, (3β,5α,6α)-; Steroidal diol intermediate
EINECS	Contact for details

Quality Control

Our 5α-Cholest-8-Ene-3β,6α-Diol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.