Description

17-α-Hydroxy-5-α-Pregnane-3,20-Dione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a critical building block for the production of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development and production of therapeutic steroids. Its defined structure and purity are essential for ensuring the efficacy and safety of the final drug products.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of various therapeutic steroid hormones and corticosteroids.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, structure-activity relationships (SAR), and developing new synthetic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis using techniques like HPLC and GC.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialized steroid derivatives for biochemical research and diagnostic applications.

Basic Information

Product Name	17-α-Hydroxy-5-α-Pregnane-3,20-Dione
CAS No.	570-59-2
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	17α-Hydroxy-5α-pregnane-3,20-dione; 5α-Pregnan-17α-ol-3,20-dione; 17-Hydroxy-5α-pregnane-3,20-dione; 17α-Hydroxyallopregnanolone; 17α-OH-DHP; Allopregnanolone 17α-ol; 3,20-Dioxo-5α-pregnan-17α-ol
EINECS	Contact for details

Quality Control

Our 17-α-Hydroxy-5-α-Pregnane-3,20-Dione is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from tests including HPLC assay, related substances, and identification. Specifications can be tailored to meet the requirements of pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.