Description

5α-Pregnane-3,20-Dione CAS NO 566-65-4 is a high-purity steroid derivative, specifically a reduced form of progesterone, serving as a critical intermediate in organic synthesis. This compound is valued for its role in the research and development of novel pharmaceutical agents and biochemical tools. It is primarily sought by manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors for use in steroid synthesis and metabolic studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs) and reference standards.
• Biochemical Research: Used as a precursor or standard in metabolic pathway studies, enzyme inhibition assays, and receptor binding research.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in custom synthesis and process development for creating specialized steroid analogs and derivatives.
• Academic & Industrial R&D: Utilized in exploratory research for developing new therapeutic compounds and diagnostic agents.

Basic Information

Product Name	5α-Pregnane-3,20-Dione
CAS No.	566-65-4
Molecular Formula	C21H32O2
Molecular Weight	316.48 g/mol
Synonyms	5α-Dihydroprogesterone; Allopregnanedione; 5α-Pregnane-3,20-dione; 3,20-Dioxo-5α-pregnane; NSC 17256; 5α-Pregnan-3,20-dione; 5α-DHP; 5α-Pregnane-3,20-dione
EINECS	209-295-8

Quality Control

Our 5α-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for research and synthesis. Certificates of Analysis (COA) detailing all test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.