Description

(17α)-3β-Hydroxypregn-5-En-20-One CAS NO 566-63-2 is a high-purity steroid intermediate, also known as Pregnenolone, which serves as a critical precursor in the biosynthesis of numerous other steroid hormones. Its value lies in providing a reliable and consistent starting material for complex synthetic pathways in pharmaceutical and research applications. This compound is essential for manufacturers and R&D laboratories in the pharmaceutical, biotechnology, and fine chemical sectors who require a high-quality building block for producing steroid-based APIs, reference standards, and other specialized biochemicals.

Application

• Pharmaceutical Intermediate: A key starting material for the synthesis of various steroid-based active pharmaceutical ingredients (APIs), including corticosteroids, progestogens, and other hormonal therapies.
• Biochemical Research: Used as a precursor in enzymatic and metabolic pathway studies to investigate steroid hormone biosynthesis and regulation.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in pharmaceutical laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex steroid derivatives for academic and industrial research purposes.
• Nutraceutical Precursor: Acts as a starting point for the production of certain dietary supplements, following strict quality and purity protocols.

Basic Information

Product Name	(17α)-3β-Hydroxypregn-5-En-20-One
CAS No.	566-63-2
Molecular Formula	C21H32O2
Molecular Weight	316.48 g/mol
Synonyms	Pregnenolone; 3β-Hydroxypregn-5-en-20-one; (3β)-3-Hydroxypregn-5-en-20-one; 5-Pregnen-3β-ol-20-one; NSC 8898; δ5-Pregnenolone; Pregn-5-ene-3β-ol-20-one
EINECS	209-296-2

Quality Control

Our (17α)-3β-Hydroxypregn-5-En-20-One is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical intermediates and research chemicals. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	+28° to +32° (c=1 in dioxane)
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.