Description

5-α-Pregnan-3-Alpha, 20-α-Diol is a high-purity steroid intermediate of significant importance in pharmaceutical research and development. This compound serves as a critical building block for the synthesis of various neurosteroids and other biologically active molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of therapeutics targeting neurological and endocrine pathways.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of neurosteroids like allopregnanolone and related analogs.
• Biochemical Research: Used as a reference standard or starting material in studies of steroid metabolism and hormone action.
• API Development: Employed in the research and development of active pharmaceutical ingredients (APIs) targeting GABA-A receptor modulation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Product Name	5-α-Pregnan-3-Alpha, 20-α-Diol
CAS No.	566-58-5
Molecular Formula	C21H36O2
Molecular Weight	320.51 g/mol
Synonyms	5α-Pregnane-3α,20α-diol; 3α,20α-Dihydroxy-5α-pregnane; Allopregnanediol; 5α-Pregnan-3α,20α-diol; 20α-Hydroxy-5α-pregnan-3α-ol
EINECS	209-295-3

Quality Control

Our 5-α-Pregnan-3-Alpha, 20-α-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.