Description

5-α-Pregnan-3-Beta, 20-α-Diol is a high-purity steroid intermediate and reference standard with the CAS number 566-56-3. This compound is critical for pharmaceutical research and development, serving as a key building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in the development of hormonal therapies, diagnostic agents, and other specialized steroid derivatives.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of steroid-based active pharmaceutical ingredients (APIs) for hormonal and anti-inflammatory therapies.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing of related steroid compounds.
• Biochemical Research: Employed in metabolic studies, enzyme inhibition assays, and research into steroid hormone pathways and receptors.
• Fine Chemical Synthesis: Serves as a versatile starting material for the custom synthesis of novel steroid derivatives and specialized chemical entities.
• Diagnostic Reagent Manufacturing: Utilized in the production of reagents and calibrators for clinical diagnostic tests measuring steroid hormone levels.

Basic Information

Product Name	5-α-Pregnan-3-Beta, 20-α-Diol
CAS No.	566-56-3
Molecular Formula	C21H36O2
Molecular Weight	320.51 g/mol
Synonyms	5α-Pregnan-3β,20α-diol; 20α-Hydroxy-5α-pregnan-3β-ol; 3β,20α-Dihydroxy-5α-pregnane; Allopregnanediol; 5α-Pregnanediol; 5α-PD; 3β,20α-Allopregnanediol
EINECS	209-291-4

Quality Control

Our 5-α-Pregnan-3-Beta, 20-α-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis to ensure it meets exacting standards for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified purity grades, typically ranging from 95% to 98%+.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.