Description

4-Pregnene-17,20Alpha,21-Triol-3,11-Dione CAS NO 566-38-1 is a high-purity steroid derivative, specifically a pregnane triol dione, serving as a critical intermediate in advanced organic synthesis. This compound matters for its role in the research and development of novel pharmaceutical agents, particularly in the steroid and hormone therapy domains. It is primarily needed by R&D laboratories, pharmaceutical manufacturers, and fine chemical synthesis companies engaged in producing specialized active pharmaceutical ingredients (APIs) and reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroid-based pharmaceuticals and hormonal agents.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing.
• Biochemical Research: Employed in metabolic pathway studies and as a precursor in the investigation of steroidogenesis and related enzymatic processes.
• Fine Chemical Synthesis: Serves as a starting material or intermediate for the custom synthesis of novel chemical entities (NCEs) and specialized derivatives in contract research and manufacturing.

Basic Information

Item	Detail
Product Name	4-Pregnene-17,20Alpha,21-Triol-3,11-Dione
CAS No.	566-38-1
Molecular Formula	C21H28O5
Molecular Weight	360.45 g/mol
Synonyms	17,20α,21-Trihydroxypregn-4-ene-3,11-dione; 20α-Hydroxycortisone; 20α-Hydroxy-11-dehydrocorticosterone; 20α-Hydroxy Kendall's Compound A; Reichstein's Substance D; 11-Dehydro-20α-hydroxycorticosterone; 4-Pregnene-17α,20α,21-triol-3,11-dione
EINECS	Contact for details

Quality Control

Our 4-Pregnene-17,20Alpha,21-Triol-3,11-Dione is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC for assay and related substances, to meet the stringent requirements of pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.