Description

5-Cholesten-3-Beta, 7-α-Diol is a key steroidal diol intermediate, also known as 7α-Hydroxycholesterol, with the CAS registry number 566-26-7. This compound is of significant value in pharmaceutical research and development, particularly as a precursor in the synthesis of bile acids and other bioactive steroids. It is essential for researchers and manufacturers in the life sciences, pharmaceutical, and fine chemical sectors who require high-purity intermediates for metabolic studies and advanced synthetic pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of primary bile acids such as chenodeoxycholic acid.
• Biochemical Research: Used as a standard or reagent in studies of cholesterol metabolism, liver function, and the 7α-hydroxylation pathway.
• Reference Standard: Serves as a high-purity analytical standard for HPLC, LC-MS, or GC-MS in clinical and research laboratories.
• Metabolite Studies: Employed in investigating oxidative stress and lipid peroxidation products related to various disease states.
• Fine Chemical Synthesis: A building block for the preparation of more complex steroidal derivatives with potential therapeutic activity.

Basic Information

Product Name	5-Cholesten-3-Beta, 7-α-Diol
CAS No.	566-26-7
Molecular Formula	C₂₇H₄₆O₂
Molecular Weight	402.66 g/mol
Synonyms	7α-Hydroxycholesterol; (3β,7α)-Cholest-5-ene-3,7-diol; 7α-HC; 5-Cholestene-3β,7α-diol; 7α-Hydroxy-cholest-5-en-3β-ol; 3β,7α-Dihydroxycholest-5-ene
EINECS	209-292-5

Quality Control

Our 5-Cholesten-3-Beta, 7-α-Diol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.