Description

7Beta-Hydroxycholestanol is a high-purity sterol derivative, specifically a hydroxylated metabolite of cholestanol. This compound is a critical intermediate and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and pharmaceutical companies focused on lipid metabolism, steroid biosynthesis, and the development of novel therapeutic agents.

Application

• Biochemical Research: Serves as a key intermediate and reference standard in studies of cholesterol metabolism and bile acid synthesis pathways.
• Pharmaceutical Development: Used as a building block or analytical standard in the research and development of sterol-based therapeutics and diagnostic agents.
• Analytical Chemistry: Employed as a high-purity calibration standard in chromatographic (HPLC, GC) and spectroscopic analyses for accurate quantification.
• Metabolite Studies: Essential for investigating metabolic disorders related to sterol and lipid processing, providing insights into disease mechanisms.
• Enzyme Activity Assays: Acts as a specific substrate or inhibitor in enzymatic studies to characterize the activity of hydroxysteroid dehydrogenases and related enzymes.

Basic Information

Product Name	7Beta-Hydroxycholestanol
CAS No.	566-25-6
Molecular Formula	C27H48O2
Molecular Weight	404.67 g/mol
Synonyms	7β-Hydroxycholestanol; (3β,5α)-Cholestane-3,7-diol; 7β-Hydroxy-5α-cholestan-3β-ol; 5α-Cholestane-3β,7β-diol; 7β-Hydroxycholestanol; 7β-Hydroxy-5α-cholestanol
EINECS	Contact for details

Quality Control

Our 7Beta-Hydroxycholestanol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and specific tests for related substances and residual solvents. We provide full traceability and a detailed Certificate of Analysis (COA) with every shipment to ensure it meets the stringent requirements of research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed immediately after use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.