Description

11α-Hydroxy-5β-Pregnane-3,20-Dione is a high-purity steroid intermediate of significant importance in pharmaceutical synthesis. This compound serves as a crucial building block for the production of more complex steroid-based active pharmaceutical ingredients (APIs). It is primarily required by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for the development and production of corticosteroids and other therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of corticosteroid drugs, including anti-inflammatory and immunosuppressive agents.
• Research & Development: Used in academic and industrial laboratories for studying steroid metabolism, enzyme activity, and structure-activity relationships (SAR).
• Reference Standard: Serves as a certified reference material (CRM) or analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Synthesis: Employed in the synthesis of specialized steroid hormones and their analogs for biological testing and clinical research.

Basic Information

Product Name	11α-Hydroxy-5β-Pregnane-3,20-Dione
CAS No.	565-93-5
Molecular Formula	C21H32O3
Molecular Weight	332.48 g/mol
Synonyms	11α-Hydroxypregnanolone; 11α-Hydroxy-5β-pregnan-3,20-dione; 11α-Hydroxy-5β-pregnane-3,20-dione; 11α-OH-5β-Pregnane-3,20-dione; 5β-Pregnane-3,20-dione, 11α-hydroxy-; 11α-Hydroxy-5β-pregnane-3,20-dione; 11α-Hydroxydihydroprogesterone; 11α-Hydroxy-5β-dihydroprogesterone
EINECS	Contact for details

Quality Control

Our 11α-Hydroxy-5β-Pregnane-3,20-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets stringent specifications for pharmaceutical-grade intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.