Description

(25R)-2α,3β-Dihydroxy-5α-Spirostan-12-One is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and functional groups make it a valuable building block for pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel steroid-based therapeutics and other specialized organic compounds.

Application

• Pharmaceutical Intermediate: A critical starting material or intermediate in the synthesis of steroidal drugs, including potential anti-inflammatory, hormonal, and cardiovascular agents.
• Research & Development: Used in academic and industrial R&D laboratories for studying steroid biosynthesis, metabolism, and structure-activity relationships (SAR).
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Fine Chemical Synthesis: Employed as a chiral precursor for the synthesis of complex natural products and other specialized organic molecules.
• Biochemical Research: Utilized in studies investigating enzyme inhibitors or modulators that interact with steroidal pathways.

Basic Information

Product Name	(25R)-2α,3β-Dihydroxy-5α-Spirostan-12-One
CAS No.	564-43-2
Molecular Formula	C27H42O5
Molecular Weight	446.62 g/mol
Synonyms	12-Ketodiosgenin; (25R)-Spirostan-12-one, 2,3-dihydroxy-, (2α,3β,5α)-; 2α,3β-Dihydroxy-5α-spirostan-12-one; Diosgenone; 12-Oxodiosgenin; 5α-Spirostan-12-one, 2α,3β-dihydroxy-, (25R)-; 12-Keto-diosgenin
EINECS	Contact for details

Quality Control

Our (25R)-2α,3β-Dihydroxy-5α-Spirostan-12-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.