Description

Bufotalinin is a potent cardiotoxic steroid derived from the skin secretions of toads within the *Bufo* genus. This high-purity compound is of significant interest in pharmacological research and development due to its specific biological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the study of cardiac glycosides, novel therapeutic agents, and natural product chemistry.

Application

• Pharmacological Research: A key reference standard and active compound for studying the mechanisms of cardiotonic steroids and their effects on Na+/K+-ATPase.
• Drug Discovery & Development: Serves as a lead compound or intermediate in the exploration of new cardiovascular or anticancer therapeutics.
• Biochemical Assays: Used in in vitro and cell-based assays to investigate cytotoxicity, apoptosis induction, and ion channel modulation.
• Natural Product Analysis: An essential analytical standard for the identification and quantification of bufadienolides in traditional medicine preparations and toad venom.
• Toxicology Studies: Employed in research to understand the toxicological profile and mechanisms of action of toad venom constituents.

Basic Information

Product Name	Bufotalinin
CAS No.	562-21-0
Molecular Formula	C26H34O6
Molecular Weight	442.55 g/mol
Synonyms	14,15β-Epoxy-3β,5β,14β-bufa-20,22-dienolide; 3β,5β,14β-Trihydroxy-19-oxo-bufa-20,22-dienolide; Bufotalin-3-hemisuccinate (common derivative reference); NSC 89225; A constituent of Ch'an Su; Toad venom poison
EINECS	Contact for details

Quality Control

Our Bufotalinin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.