Description

Pargyline CAS NO 555-57-7 is a selective and irreversible monoamine oxidase inhibitor (MAOI) belonging to the propargylamine class. This compound is of significant interest in biochemical and pharmacological research for its mechanism of action in modulating neurotransmitter levels. It serves as a critical intermediate and reference standard for the development and quality control of active pharmaceutical ingredients (APIs) and diagnostic agents. Key industries that utilize this compound include pharmaceutical R&D, contract research organizations (CROs), and academic research institutions focused on neuroscience and cardiovascular studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex monoamine oxidase inhibitors and other neuroactive compounds.
• Biochemical Research: Used as a selective, irreversible inhibitor of monoamine oxidase B (MAO-B) in enzymatic studies and mechanism-of-action investigations.
• Reference Standard: Employed as a high-purity analytical standard for quality control and assay development in pharmaceutical manufacturing.
• Neuroscience Research: A tool compound for studying the role of monoamine oxidases in neurological disorders, such as Parkinson's disease and depression.
• Metabolite Studies: Utilized in the research of drug metabolism and pharmacokinetics (DMPK) related to MAOI therapies.
• Academic & Contract Research: Supplied to universities, hospitals, and CROs for fundamental and applied research projects.

Basic Information

Product Name	Pargyline
CAS No.	555-57-7
Molecular Formula	C11H13N
Molecular Weight	159.23 g/mol
Synonyms	N-Methyl-N-2-propynylbenzylamine; Eutonyl; Pargyline Hydrochloride (salt form); N-Benzyl-N-methyl-2-propyn-1-amine; N-Methyl-N-propargylbenzylamine; (2-Propynyl)(benzyl)methylamine; NSC 72248; BRN 2207931
EINECS	209-101-1

Quality Control

Our Pargyline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR), purity assay by HPLC, and control of related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.