Description

Nebularine is a purine nucleoside analog with significant biochemical and pharmacological research applications. This compound is valued for its role as a potent adenosine deaminase inhibitor, making it a critical tool for studying nucleoside metabolism and enzyme function. It is primarily utilized by researchers in pharmaceutical development, biochemistry, and molecular biology for investigating metabolic pathways and potential therapeutic targets.

Application

• Biochemical Research: Used as a standard or reference compound in enzymatic studies, particularly for adenosine deaminase inhibition assays.
• Pharmaceutical R&D: Serves as a key intermediate or lead compound in the development of novel antiviral or anticancer agents targeting nucleoside metabolism.
• Metabolic Pathway Analysis: Employed to study purine salvage pathways and nucleotide biosynthesis in cell culture and in vitro systems.
• Enzyme Kinetics: Acts as a substrate analog to investigate the mechanism and kinetics of adenosine-modifying enzymes.
• Academic Research: Utilized in university and institutional labs for fundamental research in biochemistry and molecular pharmacology.

Basic Information

Product Name	Nebularine
CAS No.	550-33-4
Molecular Formula	C10H12N4O4
Molecular Weight	252.23 g/mol
Synonyms	9-β-D-Ribofuranosyl-9H-purin-6-amine; Purine-6-amine, 9-β-D-ribofuranosyl-; 9-β-D-Ribofuranosyladenine; Adenosine, 6-amino-9-β-D-ribofuranosyl-; 6-Amino-9-β-D-ribofuranosylpurine; 6-Aminopurine riboside; Ara-A (Note: not to be confused with Vidarabine); NSC 20164
EINECS	208-968-7

Quality Control

Our Nebularine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.