Description

3,7,12-Trihydroxycoprostane is a key intermediate in the biosynthesis of bile acids, specifically serving as a precursor in the metabolic pathway to cholic acid. This compound is of significant interest for research and development in pharmaceutical chemistry and metabolic studies. It is primarily utilized by researchers and manufacturers in the life sciences sector for biochemical synthesis, reference standard applications, and as a building block for more complex steroid derivatives.

Application

• Biochemical Research: Critical intermediate for studying bile acid biosynthesis and cholesterol metabolism pathways.
• Pharmaceutical Reference Standard: Used as a high-purity standard for analytical method development and quality control in drug discovery.
• Metabolite Synthesis: Serves as a precursor in the laboratory-scale synthesis of labeled or modified bile acid metabolites for tracer studies.
• Enzymology Studies: Employed as a substrate to investigate the activity and kinetics of specific hydroxylase and dehydrogenase enzymes.
• Academic & Industrial R&D: A valuable tool for universities and biotech companies exploring liver function, digestive processes, and related metabolic disorders.

Basic Information

Product Name	3,7,12-Trihydroxycoprostane
CAS No.	547-96-6
Molecular Formula	C27H48O3
Molecular Weight	420.67 g/mol
Synonyms	5β-Cholestane-3α,7α,12α-triol; 3α,7α,12α-Trihydroxy-5β-cholestane; 5β-Cholestane-3α,7α,12α-triol; 3α,7α,12α-Trihydroxycoprostane; Trihydroxycoprostane; Coprostanetriol; 3,7,12-Trihydroxy-5β-cholestane
EINECS	Contact for details

Quality Control

Our 3,7,12-Trihydroxycoprostane is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research applications. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.