Description

16-Epiestriol is a stereoisomer of the naturally occurring estrogen hormone estriol, distinguished by the orientation of the hydroxyl group at the C16 position. This specific configuration makes it a valuable reference standard and a key intermediate in pharmaceutical research and development, particularly for studying estrogen metabolism and receptor interactions. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors who require high-purity steroid compounds for analytical, diagnostic, and synthetic applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quality control and validation of analytical methods in drug development and manufacturing.
• Biochemical Research: Serves as a critical tool in metabolic studies, hormone research, and investigations into estrogen-related biological pathways and diseases.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key synthetic building block in the production of specialized steroid-based therapeutics.
• Diagnostic Reagent Manufacturing: Utilized in the development and calibration of immunoassays and other diagnostic kits for clinical testing.
• Academic and Institutional Research: Supports fundamental scientific studies in endocrinology, oncology, and reproductive health at universities and research institutes.

Basic Information

Product Name	16-Epiestriol
CAS No.	547-81-9
Molecular Formula	C18H24O3
Molecular Weight	288.38 g/mol
Synonyms	16-epi-Estriol; 16-Epi-Oestriol; 16α-Hydroxyestradiol; Estra-1,3,5(10)-triene-3,16α,17β-triol; 16-epi-Oestriol; 16-epi-Estriol; 16α-Estriol
EINECS	208-938-7

Quality Control

Our 16-Epiestriol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.