Description

(25R)-5α-Spirostane-2α,3β,5-Triol CAS NO 546-37-2 is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex bioactive molecules. Its defined stereochemistry and functional groups make it a valuable building block for pharmaceutical research and development. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries working on steroid-based drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical chiral starting material for the synthesis of steroidal drugs and hormones.
• Research & Development: Used in medicinal chemistry for the design and development of novel therapeutic agents targeting various receptors.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Employed in studies exploring steroid biosynthesis pathways and enzyme interactions.
• Fine Chemical Synthesis: A versatile precursor for creating specialized steroidal compounds with tailored biological activity.

Basic Information

Product Name	(25R)-5α-Spirostane-2α,3β,5-Triol
CAS No.	546-37-2
Molecular Formula	C27H44O5
Molecular Weight	448.64 g/mol
Synonyms	2α,3β,5-Trihydroxy-5α-spirostan-25R-ol; (25R)-Spirostane-2α,3β,5-triol; 5α-Spirostane-2α,3β,5-triol, (25R)-; Tigogenin-2α,3β,5-triol; (25R)-2α,3β,5-Trihydroxyspirostan-6-one (related ketone); Diosgenin triol derivative; Steroidal sapogenin triol
EINECS	Contact for details

Quality Control

Our (25R)-5α-Spirostane-2α,3β,5-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.