Description

3β,12β,14-Trihydroxy-11-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a key intermediate in the synthesis of specialized pharmaceutical compounds. Its precise stereochemistry and functional groups make it a critical building block for research and development in cardiovascular pharmacology. This compound is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers focused on developing or producing advanced therapeutic agents.

Application

• Pharmaceutical Intermediate: Primary use as a crucial precursor in the synthesis of cardioactive steroid drugs and related analogs.
• Biochemical Research: Used as a reference standard or active compound in studies of sodium-potassium ATPase inhibition and cardiac cell function.
• Medicinal Chemistry: Serves as a scaffold for the development and structure-activity relationship (SAR) studies of new therapeutic agents targeting heart conditions.
• Reference Standard: Employed in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.
• Fine Chemical Synthesis: Utilized in multi-step organic syntheses requiring a complex, stereochemically defined steroid backbone.

Basic Information

Product Name	3β,12β,14-Trihydroxy-11-Oxo-5β-Card-20(22)-Enolide
CAS No.	545-18-6
Molecular Formula	C₂₃H₃₄O₆
Molecular Weight	406.51 g/mol
Synonyms	3β,12β,14-Trihydroxy-11-oxo-5β-card-20(22)-enolide; 11-Oxodigitoxigenin; 3β,12β,14-Trihydroxy-11-oxocard-20(22)-enolide; 11-Oxo-digitoxigenin; Adonitoxigenone; 11-Ketodigitoxigenin; 11-Oxodigoxigenin; 3β,12β,14-Trihydroxy-11-oxo-5β,14β-card-20(22)-enolide
EINECS	Contact for details

Quality Control

Our 3β,12β,14-Trihydroxy-11-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, and we support compliance with cGMP and relevant pharmacopeial guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.