Description

Pentamethonium Bromide is a quaternary ammonium salt compound with significant pharmacological relevance. It serves as a classic non-depolarizing neuromuscular blocking agent and ganglionic blocker, primarily used in research to study autonomic nervous system functions. This high-purity compound is essential for pharmaceutical R&D, academic research, and the development of analytical reference standards. Pentamethonium Bromide CAS NO 541-20-8 is a critical material for investigators in neuropharmacology and anesthesiology.

Application

• Pharmacological Research: Used as a standard nicotinic acetylcholine receptor (nAChR) antagonist to study neuromuscular and ganglionic transmission.
• Reference Standard: Serves as a high-purity analytical standard in quality control laboratories for method development and validation.
• Academic & Biomedical Research: A key tool compound in university and institutional labs for investigating autonomic nervous system physiology and pharmacology.
• Drug Discovery & Development: Employed in early-stage research for screening and characterizing new compounds targeting cholinergic pathways.
• Biochemical Assays: Utilized in in vitro assays to block specific receptor subtypes and elucidate signal transduction mechanisms.

Basic Information

Product Name	Pentamethonium Bromide
CAS No.	541-20-8
Molecular Formula	C12H30Br2N2
Molecular Weight	362.19 g/mol
Synonyms	Pentamethonium Dibromide; 1,5-Bis(trimethylammonio)pentane Dibromide; Pentamethylene-1,5-bis(trimethylammonium) Dibromide; NSC 25159; Pentamethonium Bromide; Pentamethonium (as bromide)
EINECS	Contact for details

Quality Control

Our Pentamethonium Bromide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.