Description

Dibenzylphosphoryl Chloride is a versatile organophosphorus reagent primarily used as a key phosphorylating and coupling agent in synthetic chemistry. Its high reactivity makes it invaluable for introducing the dibenzylphosphoryl group, a common protecting group in nucleotide and peptide synthesis. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of nucleotide analogs, prodrugs, and antiviral/anticancer agents.
• Peptide Chemistry: Used as a phosphorylating agent for the protection of hydroxyl groups in complex peptide synthesis.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of certain organophosphate-based insecticides and plant growth regulators.
• Ligand and Catalyst Preparation: Employed in the synthesis of phosphine ligands and metal-organic frameworks (MOFs) for catalytic applications.
• Polymer Modification: Facilitates the functionalization of polymers to introduce phosphate groups, altering material properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new phosphorylation methodologies.

Basic Information

Product Name	Dibenzylphosphoryl Chloride
CAS No.	538-37-4
Molecular Formula	C14H14ClO2P
Molecular Weight	280.69 g/mol
Synonyms	Dibenzyl Phosphorochloridate; Dibenzyl Chlorophosphate; Chlorophosphoric Acid Dibenzyl Ester; Dibenzyloxyphosphoryl Chloride; DBPC; (Benzyloxy)phosphoryl Dichloride (partial hydrolysis product); Phosphorochloridic Acid, Bis(phenylmethyl) Ester
EINECS	208-688-6

Quality Control

Our Dibenzylphosphoryl Chloride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and production. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.