Description

2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Propan-2-Ol is a high-value fluorinated aromatic alcohol building block. This compound matters for its unique trifluoromethyl and fluoro substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by pharmaceutical R&D and agrochemical manufacturers for the synthesis of advanced active ingredients and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in CNS, anti-inflammatory, and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Polymer Science: Employed as a monomer or modifier to introduce fluorine into polymer backbones, enhancing chemical resistance and lowering surface energy.
• Organic Electronics: Acts as a building block for electron-transport materials and hole-blocking layers in OLEDs and other organic electronic devices.
• Chemical Research: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex, multi-substituted aromatic systems.

Basic Information

Product Name	2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Propan-2-Ol
CAS No.	534-39-4
Molecular Formula	C10H10F4O
Molecular Weight	222.18 g/mol
Synonyms	1-(4-Fluoro-3-(trifluoromethyl)phenyl)propan-2-ol; 2-Propanol, 1-[4-fluoro-3-(trifluoromethyl)phenyl]-; α,α-Bis(trifluoromethyl)-4-fluorobenzyl alcohol; 4-Fluoro-α,α-bis(trifluoromethyl)benzyl alcohol; 2-(4-Fluoro-3-trifluoromethylphenyl)isopropanol; 1-(4-Fluoro-3-trifluoromethylphenyl)-2-propanol; F3C-Ph-F Alcohol Derivative
EINECS	Contact for details

Quality Control

Our 2-[4-Fluoro-3-(Trifluoromethyl)Phenyl]Propan-2-Ol is manufactured under strict quality management systems. We provide material with typical purity grades from 97% to 99.5% (HPLC), tailored to your process requirements. Every batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment ensures compliance with relevant ICH guidelines and supports your regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0% - 99.5%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.