Description

Metycaine Hydrochloride CAS NO 533-28-8 is a synthetic local anesthetic compound, chemically known as 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride. This pharmaceutical-grade active ingredient is valued for its reliable anesthetic properties and stability in formulation. It is primarily utilized by manufacturers in the pharmaceutical and life sciences industries for the development and production of injectable and topical anesthetic preparations.

Application

• Pharmaceutical Manufacturing: Key intermediate or active pharmaceutical ingredient (API) in the synthesis of local anesthetic formulations.
• Injectable Anesthetics: Used in the production of solutions for infiltration, nerve block, and spinal anesthesia.
• Topical Preparations: Incorporated into creams, ointments, or gels for surface anesthesia.
• Ophthalmic Solutions: Component in eye drop formulations for corneal anesthesia during diagnostic procedures.
• Veterinary Medicine: Used in anesthetic products for animal healthcare.
• Research & Development: Serves as a reference standard and building block in pharmacological and medicinal chemistry research.

Basic Information

Product Name	Metycaine Hydrochloride
CAS No.	533-28-8
Molecular Formula	C17H28N2O3·HCl
Molecular Weight	344.88 g/mol
Synonyms	Piperocaine Hydrochloride; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate hydrochloride; 3-Amino-4-propoxybenzoic acid 2-(diethylamino)ethyl ester hydrochloride; Neothesin; Metycaine; α-Piperidin-o-cresol methyl ether hydrochloride; Contact for details for additional trade names.
EINECS	208-567-8

Quality Control

Our Metycaine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Specifications typically align with pharmacopeial requirements. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture sources to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.