Description

5-Pregnen-3-Beta, 16-α-Diol-20-One is a high-purity steroid intermediate, also known as 16α-Hydroxypregnenolone, with the CAS registry number 520-88-7. This compound is a critical building block in the synthesis of more complex steroid hormones and active pharmaceutical ingredients (APIs). It is essential for research and development laboratories, as well as production facilities, in the pharmaceutical and fine chemical industries that require reliable, high-quality steroid precursors.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the multi-step synthesis of corticosteroid and other steroid-based APIs.
• Research & Development: Used in academic and industrial R&D for studying steroid metabolism, enzyme activity, and developing new therapeutic compounds.
• Fine Chemical Synthesis: Serves as a chiral building block for the production of specialized fine chemicals and reference standards.
• Biochemical Studies: Utilized in metabolic pathway research and as a substrate or inhibitor in enzymatic assays related to steroidogenesis.

Basic Information

Product Name	5-Pregnen-3-Beta, 16-α-Diol-20-One
CAS No.	520-88-7
Molecular Formula	C₂₁H₃₂O₃
Molecular Weight	332.48 g/mol
Synonyms	16α-Hydroxypregnenolone; 3β,16α-Dihydroxypregn-5-en-20-one; Pregnenolone, 16α-hydroxy-; 5-Pregnene-3β,16α-diol-20-one; 16α-Hydroxy-δ⁵-pregnenolone; 16α-OH-Pregnenolone; 3β,16α-Dihydroxy-5-pregnen-20-one
EINECS	208-300-1

Quality Control

Our 5-Pregnen-3-Beta, 16-α-Diol-20-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) detailing all specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.