Description

5-α-Cholestan-3-α-Ol is a high-purity sterol derivative, also known as cholestanol, which serves as a critical reference standard and intermediate in advanced chemical synthesis. Its defined stereochemistry and purity make it an essential building block for research and development in the pharmaceutical and life sciences sectors. This compound is particularly valuable for scientists and manufacturers working on steroid chemistry, lipid metabolism studies, and the production of specialized biochemical reagents.

Application

• Pharmaceutical Reference Standard: Used as a certified standard for analytical methods (HPLC, GC-MS) in quality control and research laboratories.
• Biochemical Research: Serves as a key intermediate in the study of cholesterol biosynthesis, metabolism, and related metabolic pathways.
• Steroid Synthesis: Acts as a chiral starting material or intermediate for the synthesis of more complex steroid analogs and hormone derivatives.
• Diagnostic Reagent Manufacturing: Utilized in the formulation of calibration kits and reagents for clinical diagnostics, particularly in lipid profiling.
• Academic & Industrial R&D: Employed in basic research exploring membrane biology, lipid rafts, and the physicochemical properties of sterols.

Basic Information

Product Name	5-α-Cholestan-3-α-Ol
CAS No.	516-95-0
Molecular Formula	C₂₇H₄₈O
Molecular Weight	388.67 g/mol
Synonyms	Cholestanol; Dihydrocholesterol; 5α-Cholestan-3β-ol (common numbering); 3β-Hydroxy-5α-cholestane; Allocholestanol; Coprostanol (isomer); NSC 8798; Stanol
EINECS	208-238-3

Quality Control

Our 5-α-Cholestan-3-α-Ol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity assays and identity confirmation, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	140 - 145 °C
Loss on Drying	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.