Description

3Beta,14,16Beta-Trihydroxy-5Beta-Card-20(22)-Enolide 16-Formate is a high-purity cardenolide derivative, a key intermediate in the synthesis of specialized cardiac glycosides and other bioactive steroidal compounds. Its precise chemical structure makes it a critical building block for pharmaceutical research and development, where consistent quality and reliable supply are paramount. This compound is essential for manufacturers and research institutions in the pharmaceutical, biotechnology, and fine chemical sectors focused on cardiovascular drug discovery and advanced organic synthesis. CAS No. 514-21-6.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex cardiac glycosides and other steroidal active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and a key reagent in studies investigating the structure-activity relationships of cardenolides.
• Fine Chemical Synthesis: Serves as a specialized building block for the production of novel steroidal compounds with potential therapeutic applications.
• Academic & Contract Research: Employed in university and CRO laboratories for medicinal chemistry projects and pathway elucidation.

Basic Information

Item	Details
Product Name	3Beta,14,16Beta-Trihydroxy-5Beta-Card-20(22)-Enolide 16-Formate
CAS No.	514-21-6
Molecular Formula	C₂₄H₃₄O₇
Molecular Weight	434.52 g/mol
Synonyms	Digitoxigenin 16-formate; 3β,14β,16β-Trihydroxy-5β-card-20(22)-enolide 16-formate; 16-Formyldigitoxigenin; 16β-Formyloxy-3β,14β-dihydroxy-5β-card-20(22)-enolide; 3β,14β-Dihydroxy-16β-formyloxy-5β-card-20(22)-enolide; 16-O-Formyldigitoxigenin; 16β-Formyloxydigitoxigenin; Digitoxigenin, 16-formate
EINECS	208-170-9

Quality Control

Our 3Beta,14,16Beta-Trihydroxy-5Beta-Card-20(22)-Enolide 16-Formate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.