Description

(25R)-5Alpha-Spirostan-2Alpha,3Beta-Diol is a high-purity steroidal sapogenin derivative, a key intermediate in the synthesis of complex steroid-based pharmaceuticals and bioactive compounds. Its defined stereochemistry at the 2, 3, and 25 positions makes it a critical chiral building block for ensuring the biological efficacy of final products. This compound is essential for research and development laboratories, as well as production facilities, in the pharmaceutical, agrochemical, and advanced materials sectors seeking to develop or manufacture novel steroid-derived actives.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of steroidal drugs, including certain hormones, anti-inflammatory agents, and cardiovascular therapeutics.
• Research & Development: Used in academic and industrial R&D for studying steroid biosynthesis, structure-activity relationships (SAR), and developing new bioactive molecules.
• Agrochemical Synthesis: Serves as a starting material for creating novel plant growth regulators or environmentally benign pesticides with steroidal frameworks.
• Reference Standard: Employed as an analytical standard in quality control laboratories for HPLC, GC, or TLC methods to identify and quantify related steroidal compounds.
• Biochemical Studies: Utilized in enzymatic studies and metabolic pathway research related to sterol and sapogenin metabolism.
• Fine Chemical Synthesis: Acts as a versatile intermediate for the production of specialty chemicals and advanced materials requiring a rigid, polycyclic backbone.

Basic Information

Product Name	(25R)-5Alpha-Spirostan-2Alpha,3Beta-Diol
CAS No.	511-96-6
Molecular Formula	C27H44O4
Molecular Weight	432.64 g/mol
Synonyms	Diosgenin derivative; (25R)-Spirostan-2α,3β-diol; 2α,3β-Dihydroxy-5α-spirostan; 5α-Spirostane-2α,3β-diol; Tigogenin diol; (2α,3β,5α,25R)-Spirostane-2,3-diol; Neotigogenin
EINECS	Contact for details

Quality Control

Our (25R)-5Alpha-Spirostan-2Alpha,3Beta-Diol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical quality attributes to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.