Description

3β-Hydroxy-5β-Carda-14,16,20(22)-Trienolide is a high-purity, specialized cardenolide compound, a class of natural products known for their potent biological activity. This compound serves as a critical reference standard and advanced pharmaceutical intermediate for research and development in medicinal chemistry. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis (HPLC, LC-MS) of cardenolide-based drugs and natural extracts in quality control laboratories.
• Medicinal Chemistry Research: Serves as a key synthetic intermediate or a lead compound scaffold for the development of new cardioactive or anticancer agents.
• Biochemical Research: Employed in studies investigating the mechanism of action of cardiac glycosides on sodium-potassium ATPase pumps.
• Natural Product Isolation & Standardization: Acts as a benchmark for the identification and purification of related cardenolides from botanical sources like Digitalis species.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies of steroidal lactones.

Basic Information

Product Name	3β-Hydroxy-5β-Carda-14,16,20(22)-Trienolide
CAS No.	511-17-1
Molecular Formula	C23H32O4
Molecular Weight	372.50 g/mol
Synonyms	3β-Hydroxy-5β-card-14,16,20(22)-trienolide; 14,16-Didehydro-3β-hydroxy-5β-card-20(22)-enolide; 3β-Hydroxy-14,16-didehydro-5β-card-20(22)-enolide; 3-Epigitoxigenin; 3-Epi-gitoxigenin; 3-Epigitoxigenin (8CI); Card-14,16,20(22)-trienolide, 3-hydroxy-, (3β,5β)-
EINECS	Contact for details

Quality Control

Our 3β-Hydroxy-5β-Carda-14,16,20(22)-Trienolide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are available upon request for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing under an inert atmosphere at -20°C to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.