Description

3β,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is a high-purity cardiac glycoside derivative, a key intermediate in the synthesis of potent pharmaceutical compounds. Its precise stereochemistry and functional groups make it a critical building block for research and development in cardiovascular therapeutics. This compound is essential for pharmaceutical manufacturers, research institutions, and fine chemical suppliers focused on developing and producing advanced cardiac drugs.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor for the production of cardiac glycoside drugs, including digoxin and digitoxin analogs.
• Biochemical Research: Used as a reference standard and active compound in studies investigating sodium-potassium ATPase (Na⁺/K⁺-ATPase) inhibition and cardiac muscle contractility.
• Medicinal Chemistry: Serves as a core scaffold for the structural modification and development of new therapeutic agents targeting heart failure and arrhythmias.
• Analytical Standard: Employed in high-performance liquid chromatography (HPLC) and mass spectrometry (MS) for method development, validation, and quality control of related pharmaceutical products.
• Academic Research: Utilized in university and institutional labs for pharmacological and toxicological studies of cardenolide compounds.

Basic Information

Product Name	3β,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide
CAS No.	510-63-4
Molecular Formula	C₂₃H₃₂O₆
Molecular Weight	404.50 g/mol
Synonyms	Digitoxigenin; 3β,14-Dihydroxy-5β-card-20(22)-enolide; 19-Oxodigitoxigenin; 3β,14-Dihydroxy-19-oxo-5β,20(22)-cardenolide; 19-Oxo-3β,14-dihydroxy-5β-card-20(22)-enolide; Card-20(22)-enolide, 3,14-dihydroxy-19-oxo-, (3β,5β)-; Strophanthidin aglycone derivative
EINECS	208-108-7

Quality Control

Our 3β,14-Dihydroxy-19-Oxo-5β-Card-20(22)-Enolide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical intermediate grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.