Description

3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is a high-purity bufadienolide compound, a class of steroids with significant biological activity. This product is valued for its role as a critical reference standard and active pharmaceutical ingredient (API) intermediate in research and development. It is essential for pharmaceutical manufacturers, biotechnology research labs, and academic institutions focused on cardiovascular and oncology drug discovery.

Application

• Pharmaceutical Reference Standard: Used for the qualitative and quantitative analysis of bufadienolide-containing drugs and natural products.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic building block in the production of specialized cardiac and anticancer therapeutics.
• Biochemical Research: Employed in studies investigating Na+/K+-ATPase inhibition and its associated signaling pathways.
• Natural Product Isolation & Standardization: Acts as a benchmark compound for the quality control of traditional medicine extracts, such as Chan Su or toad venom.
• Preclinical Drug Development: Utilized in in vitro and in vivo studies to evaluate efficacy, toxicity, and pharmacokinetic profiles.

Basic Information

Product Name	3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide
CAS No.	510-62-3
Molecular Formula	C₂₄H₃₂O₆
Molecular Weight	416.51 g/mol
Synonyms	19-Oxocinobufagin; 19-Oxocinobufogenin; 3β,14-Dihydroxy-19-oxobufa-4,20,22-trienolide; Bufadienolide CPD 1; Arenobufagin 19-aldehyde; 19-Oxo-cinobufagin; 19-Oxocinobufogenin
EINECS	Contact for details

Quality Control

Our 3β,14-Dihydroxy-19-Oxobufa-4,20,22-Trienolide is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for research and pharmaceutical use. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.