Description

6β-(Acetyloxy)-3β,8,14-Trihydroxybufa-4,20,22-Trienolide is a specific bufadienolide derivative, a class of naturally occurring steroid-like compounds with significant biological activity. This high-purity reference standard is critical for research and development in the pharmaceutical and life sciences sectors, where precise molecular characterization is paramount. It is primarily utilized by researchers and quality control laboratories focused on cardiac glycosides, natural product chemistry, and the development of novel therapeutic agents.

Application

• Pharmaceutical Reference Standard: Serves as a certified standard for the identification, purity assessment, and quantification of bufadienolides in drug development and quality control processes.
• Biochemical Research: Used as a key reagent in studies investigating the mechanism of action, structure-activity relationships (SAR), and metabolic pathways of cardiac glycosides.
• Natural Product Analysis: Essential for the analysis and standardization of traditional medicines or botanical extracts containing toad venom or other bufadienolide sources.
• Academic Research: Employed in university and institutional labs for pharmacological studies, toxicology research, and synthetic chemistry projects.
• Analytical Method Development: Acts as a critical component for developing and validating analytical methods such as HPLC, LC-MS, and NMR for bufadienolide detection.

Basic Information

Product Name	6β-(Acetyloxy)-3β,8,14-Trihydroxybufa-4,20,22-Trienolide
CAS No.	507-59-5
Molecular Formula	C₂₆H₃₄O₈
Molecular Weight	474.55 g/mol
Synonyms	6β-Acetoxy-3β,8,14-trihydroxybufa-4,20,22-trienolide; 3β,8,14-Trihydroxy-6β-(acetyloxy)bufa-4,20,22-trienolide; Bufalin 6-acetate; 6β-Acetoxybufalin; 6-O-Acetylbufalin; Bufadienolide derivative; Gamabufotalin 6-acetate (related); Telocinobufagin 6-acetate (related)
EINECS	Contact for details

Quality Control

Our 6β-(Acetyloxy)-3β,8,14-Trihydroxybufa-4,20,22-Trienolide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles. We support compliance with ISO 9001 standards and can provide materials tailored to specific research or analytical requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the certificate of analysis. Keep the container in a dry, cool, and well-ventilated area. For long-term storage, consider storing under inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.