Description

Carbimazole is a thioimidazole derivative and a prodrug of methimazole, primarily used as an antithyroid agent. Its core value lies in its ability to effectively manage hyperthyroidism by inhibiting the synthesis of thyroid hormones. This makes it a critical active pharmaceutical ingredient (API) for manufacturers of prescription medications. Industries requiring this compound include the global pharmaceutical sector for the formulation of anti-thyroid tablets and related therapeutic products.

Application

• Primary Active Pharmaceutical Ingredient (API) in anti-thyroid medications for treating hyperthyroidism (overactive thyroid).
• Key intermediate in the synthesis of related thioimidazole-based therapeutic agents.
• Used in clinical research and development of novel thyroid disorder treatments.
• Essential component in the production of generic and branded prescription drugs worldwide.
• Reference standard in analytical laboratories for quality control and pharmaceutical testing.

Basic Information

Product Name	Carbimazole
CAS No.	22232-54-8
Molecular Formula	C7H10N2O2S
Molecular Weight	186.23 g/mol
Synonyms	Carbimazole; Neomercazole; 3-Methyl-2-thioxo-4-imidazoline-1-carboxylic acid ethyl ester; Ethyl 3-methyl-2-thioxo-4-imidazoline-1-carboxylate; Bimazol; Carbotiroid; Neo-Thyreostat; N-Mercaptoimidazole ethyl carbonate; CAS 22232-54-8
EINECS	244-874-6

Quality Control

Our Carbimazole is produced under strict quality management systems to ensure it meets the high standards required for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, referencing pharmacopeial standards such as USP, EP, or BP where applicable. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee product consistency and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.