Description

6-Azauridine is a synthetic pyrimidine nucleoside analog with significant biochemical and pharmacological research applications. This compound is valued for its ability to interfere with nucleic acid metabolism, making it a critical tool for studying enzyme inhibition and cellular processes. It is primarily utilized by research institutions and pharmaceutical developers in the fields of antiviral research, oncology studies, and biochemical assay development.

Application

• Biochemical Research: Used as a selective inhibitor of orotidine-5'-monophosphate decarboxylase (OMP decarboxylase) to study the de novo pyrimidine biosynthesis pathway.
• Antiviral Studies: Investigated for its potential activity against various viral agents due to its mechanism of disrupting RNA synthesis.
• Oncology Research: Serves as a reference compound in cancer research to explore the effects of nucleotide analogs on tumor cell proliferation.
• Enzyme Kinetics: Employed in enzymatic assays to determine kinetic parameters and inhibition constants for related enzymes.
• Pharmaceutical Intermediate: Acts as a key starting material or intermediate in the synthesis of more complex nucleoside-based therapeutic agents.
• Academic & Diagnostic Use: Utilized in university laboratories and diagnostic kit development for metabolic disorder studies.

Basic Information

Product Name	6-Azauridine
CAS No.	54-25-1
Molecular Formula	C8H11N3O6
Molecular Weight	245.19 g/mol
Synonyms	6-Azauracil riboside; Azauracil riboside; 1-β-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione; 6-Azuridine; NSC-32074; 6-AZUR; Azaribine metabolite; 6-Aza-Urd
EINECS	200-200-5

Quality Control

Our 6-Azauridine is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, to ensure it meets the high standards required for research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.