Description

3-Deoxyestrone is a key steroid intermediate and metabolite of significant interest in pharmaceutical research and development. This compound is valued for its role as a precursor and reference standard in the synthesis and analysis of more complex steroidal molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from drug discovery to quality control.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of steroidal drugs and hormones.
• Biochemical Research: Used as a reference standard and metabolite in studies investigating estrogen biosynthesis, metabolism, and related endocrine pathways.
• Analytical Standard: Employed in quality control laboratories for method development, calibration, and impurity profiling via techniques like HPLC and GC-MS.
• Academic & Contract Research: Essential for basic research in universities and CROs (Contract Research Organizations) focusing on steroid chemistry and pharmacology.

Basic Information

Product Name	3-Deoxyestrone
CAS No.	53-45-2
Molecular Formula	C18H22O2
Molecular Weight	270.37 g/mol
Synonyms	19-Nor-5(10)-androsten-3,17-dione; 3-Deoxy-19-nor-δ5(10)-androsten-17-one; Estrone, 3-deoxy-; 5(10)-Estren-17-one, 3-hydroxy-; 3-Desoxyestrone; 3-Deoxy-oestrone
EINECS	Contact for details

Quality Control

Our 3-Deoxyestrone is produced and handled under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.