Description

Propylthiouracil CAS NO 51-52-5 is a thiourea derivative that acts as a potent antithyroid agent by inhibiting the enzyme thyroid peroxidase. This compound is critical for the management of hyperthyroidism, particularly in patients requiring precise control of thyroid hormone synthesis. It is an essential active pharmaceutical ingredient (API) for pharmaceutical manufacturers and research institutions developing and producing antithyroid medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in medications for treating hyperthyroidism and Graves' disease.
• Clinical Research: Used in preclinical and clinical studies to investigate thyroid function and metabolic disorders.
• Veterinary Medicine: Application in the treatment of hyperthyroidism in companion animals, such as cats.
• Biochemical Research: Serves as a specific inhibitor in enzymatic studies related to thyroid hormone biosynthesis.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for drug testing and verification.

Basic Information

Product Name	Propylthiouracil
CAS No.	51-52-5
Molecular Formula	C7H10N2OS
Molecular Weight	170.23 g/mol
Synonyms	6-Propyl-2-thiouracil; 6-n-Propylthiouracil; PTU; Propacil; Propyl-thyracil; Thyracil; 2-Thio-6-propylpyrimidin-4(1H)-one; 4-Hydroxy-2-mercapto-6-propylpyrimidine; 6-Propyl-2-sulfanylpyrimidin-4-ol; Antityroid
EINECS	200-103-2

Quality Control

Our Propylthiouracil is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with in-house specifications and relevant pharmacopeial guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.