Description

5-Bromouracil (CAS NO 51-20-7) is a halogenated pyrimidine derivative that serves as a critical building block and research tool in life sciences. Its primary value lies in its ability to act as a thymine analog, making it a fundamental compound for studying mutagenesis, DNA replication, and nucleic acid biochemistry. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors, particularly for developing novel therapeutic agents and advanced molecular probes.

Application

• Pharmaceutical Research & Development: Used as a key intermediate in the synthesis of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Employed as a mutagenic base analog in molecular biology to study DNA replication errors, repair mechanisms, and genetic mutations.
• Agrochemical Synthesis: Serves as a precursor in the development of certain herbicides and plant growth regulators.
• Diagnostic Reagents: Incorporated into probes and assays for genetic testing and microbiological research.
• Academic & Institutional Research: A standard reagent for university and institutional labs focusing on genetics, biochemistry, and molecular biology.

Basic Information

Product Name	5-Bromouracil
CAS No.	51-20-7
Molecular Formula	C4H3BrN2O2
Molecular Weight	190.98 g/mol
Synonyms	5-BrU; 5-Bromo-1H-pyrimidine-2,4-dione; 5-Bromo-2,4(1H,3H)-pyrimidinedione; Bromouracil; 5-Bromouracil, 98+%; NSC 3829; BU
EINECS	200-078-4

Quality Control

Our 5-Bromouracil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and melting point determination, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	293°C - 297°C (decomposes)
Loss on Drying	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.