Description

1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methyl-Pyrimidine-2,4-Dione is a high-purity nucleoside derivative essential for advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and reference standard in the synthesis and study of nucleic acid analogs. It is primarily required by research institutions, diagnostic manufacturers, and pharmaceutical companies engaged in antiviral and anticancer drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, metabolic pathway analysis, and molecular biology experiments.
• Diagnostic Reagent Manufacturing: Employed in the production of high-sensitivity assay kits and probes for genetic testing and virology.
• Academic Research: Fundamental material for university and institutional research into nucleic acid chemistry, enzymology, and drug mechanisms of action.
• Standards and Metrology: Serves as a certified reference material (CRM) for quality control and analytical method validation in regulated laboratories.

Basic Information

Product Name	1-[(2R,4S,5R)-4-Hydroxy-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methyl-Pyrimidine-2,4-Dione
CAS No.	50-88-4
Molecular Formula	C10H14N2O5
Molecular Weight	242.23 g/mol
Synonyms	Thymidine; 1-(2-Deoxy-β-D-ribofuranosyl)thymine; 2'-Deoxythymidine; dT; D-Thymidine; 5-Methyl-2'-deoxyuridine; NSC 21548; Thymine deoxyriboside
EINECS	200-070-4

Quality Control

Our Thymidine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for stereochemical integrity, and stringent controls for residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and pharmaceutical-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	-20° to -24° (c=1 in H2O)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.