Description

Phentolamine CAS NO 50-60-2 is a non-selective α-adrenergic receptor antagonist. This compound is a critical pharmaceutical intermediate and research chemical, valued for its potent vasodilatory effects. It is primarily required by pharmaceutical manufacturers, research institutions, and chemical synthesis facilities for the development and production of cardiovascular medications and for use in biochemical research.

Application

• Pharmaceutical Active Ingredient: Key intermediate in the synthesis of medications for hypertension and pheochromocytoma.
• Biochemical Research: Used as a standard α-adrenergic blocker in receptor binding studies and pharmacological experiments.
• Diagnostic Agent: Employed in diagnostic tests for autonomic nervous system function.
• Vasodilator Formulations: A component in formulations used to treat vasospastic conditions and to reverse the effects of local anesthetics containing vasoconstrictors.
• Chemical Synthesis: Serves as a building block for the preparation of more complex adrenergic compounds and analogs.

Basic Information

Product Name	Phentolamine
CAS No.	50-60-2
Molecular Formula	C17H19N3O
Molecular Weight	281.35 g/mol
Synonyms	Phentolamine Mesylate (common salt form); Regitine; Phentolamine Hydrochloride; 3-[(4,5-Dihydro-1H-imidazol-2-yl)methylamino]phenol; 2-[[N-(m-Hydroxyphenyl)-p-toluidino]methyl]-2-imidazoline; Phentolaminum; Phentolamin; Fentolamina
EINECS	200-055-5

Quality Control

Our Phentolamine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC and other validated methods. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with relevant standards for pharmaceutical intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, protect from moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.