Description

Corticosterone CAS NO 50-22-6 is a naturally occurring steroid hormone, also known as compound B, which plays a crucial role in the regulation of metabolism, immune response, and stress. As a key intermediate in the biosynthesis of aldosterone and other corticosteroids, it is of significant importance in biochemical research and pharmaceutical development. This compound is essential for laboratories and manufacturers focused on endocrinology, steroid chemistry, and the production of reference standards or active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A critical precursor in the synthetic pathways for manufacturing glucocorticoids, mineralocorticoids, and other steroid-based therapeutics.
• Biochemical Research: Used as a reference standard and reagent in studies investigating the hypothalamic-pituitary-adrenal (HPA) axis, stress physiology, and metabolic regulation.
• Diagnostic Development: Serves as a calibrator or antigen in the development of immunoassays and diagnostic kits for measuring corticosteroid levels.
• Endocrinology Studies: Employed in in vitro and in vivo research to understand the mechanisms of action and physiological effects of endogenous corticosteroids.
• Veterinary Medicine: Used in research and development for animal health products related to stress and metabolic disorders.

Basic Information

Product Name	Corticosterone
CAS No.	50-22-6
Molecular Formula	C21H30O4
Molecular Weight	346.46 g/mol
Synonyms	11β,21-Dihydroxypregn-4-ene-3,20-dione; 17-Deoxycortisol; Compound B; Kendall's Compound B; Reichstein's Substance H; 4-Pregnene-11β,21-diol-3,20-dione; 11β-Hydroxycorticosterone
EINECS	200-019-7

Quality Control

Our Corticosterone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets high-purity standards suitable for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.