Description

4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carbonyl Chloride is a high-purity, reactive chemical intermediate essential for advanced organic synthesis. Its core value lies in its role as a versatile acylating agent and key building block for constructing complex heterocyclic scaffolds. This compound is critically needed by pharmaceutical R&D teams and fine chemical manufacturers developing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated benzoxazine-based molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel benzoxazine-based drug candidates, including potential central nervous system (CNS) agents and antimicrobials.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides with complex heterocyclic structures.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and specialty materials.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, particularly in amide bond formation and heterocycle construction.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.

Basic Information

Product Name	4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carbonyl Chloride
CAS No.	499770-73-9
Molecular Formula	C10H10ClNO2
Molecular Weight	211.65 g/mol
Synonyms	7-(Chlorocarbonyl)-4-methyl-3,4-dihydro-2H-1,4-benzoxazine; 4-Methyl-2H-1,4-benzoxazine-7-carbonyl chloride, 3,4-dihydro-; 1,4-Benzoxazine-7-carbonyl chloride, 3,4-dihydro-4-methyl-; 4-Methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine-7-carbonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-3,4-Dihydro-2H-1,4-Benzoxazine-7-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.