Description

2,4-Dibromo-6-Fluorobenzoyl Chloride is a high-purity, multi-functional aromatic acid chloride building block. This compound is critical for introducing the 2,4-dibromo-6-fluorobenzoyl moiety into target molecules, enabling precise structural modifications. It is primarily utilized by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the halogenated benzoyl structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the synthesis of monomers and functionalized polymers with specific electronic or optical properties.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom chemical synthesis services catering to R&D and scale-up projects.
• Fluorescent Dye and Sensor Chemistry: Used to construct complex fluorophores and molecular sensors due to its halogenated aromatic core.

Basic Information

Item	Details
Product Name	2,4-Dibromo-6-Fluorobenzoyl Chloride
CAS No.	497181-20-1
Molecular Formula	C7H2Br2ClFO
Molecular Weight	316.35 g/mol
Synonyms	6-Fluoro-2,4-dibromobenzoyl chloride; 2,4-Dibromo-6-fluorobenzoic acid chloride; Benzoyl chloride, 2,4-dibromo-6-fluoro-; 2,4-Dibromo-6-fluorobenzoic acid chloride; 497181-20-1; 2,4-Dibromo-6-fluoro-benzoyl chloride
EINECS	Contact for details

Quality Control

Our 2,4-Dibromo-6-Fluorobenzoyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, and our quality management system supports compliance with cGMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.