Description

1-Piperidinecarbonyl Chloride, 4-(Acetyloxy)- (9Ci) is a specialized organic intermediate featuring a reactive acid chloride group and a protected hydroxyl moiety. This compound is critical for the efficient synthesis of complex molecules, particularly in pharmaceutical research and development. It serves as a key building block for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to introduce piperidine-based pharmacophores.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that require piperidine scaffolds.
• Chemical Research & Development: Employed as a versatile building block for constructing complex heterocyclic compounds in academic and industrial R&D labs.
• Peptidomimetic Chemistry: Facilitates the introduction of modified amino acid structures in the design of peptide-based therapeutics.
• Ligand Synthesis for Catalysis: Used to create sophisticated ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific functional properties.

Basic Information

Product Name	1-Piperidinecarbonyl Chloride, 4-(Acetyloxy)- (9Ci)
CAS No.	496052-32-5
Molecular Formula	C8H12ClNO3
Molecular Weight	205.64 g/mol
Synonyms	4-(Acetyloxy)piperidine-1-carbonyl chloride; 4-Acetoxypiperidine-1-carbonyl chloride; 1-Carbamoyl-4-acetoxypiperidinium chloride (alternative form); 4-Acetyloxypiperidine-1-carboxylic acid chloride; 4-Acetoxy-1-piperidinecarbonyl chloride; N-Carboxy-4-acetoxypiperidine chloride; 4-Acetoxy-piperidine-1-carbonyl chloride; 1-Piperidinecarbonyl chloride, 4-(acetyloxy)-
EINECS	Contact for details

Quality Control

Our 1-Piperidinecarbonyl Chloride, 4-(Acetyloxy)- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from strong acids and organic solvents.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.