Description

4-Oh-E1-1-N3Ade CAS NO 488841-24-3 is a specialized nucleoside analog with significant potential in advanced pharmaceutical research and development. This compound is valued for its role as a key intermediate or building block in the synthesis of novel therapeutic agents, particularly in antiviral and anticancer drug discovery pipelines. It is primarily sought by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in developing next-generation nucleotide-based therapies.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel nucleoside-based antiviral and anticancer drug candidates.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to understand biological pathways and mechanisms of action.
• Proteomics & Genomics: Employed in the development of probes and tools for studying nucleic acid interactions and modifications.
• Antiviral Drug Development: Investigated for its potential incorporation into oligonucleotide sequences targeting specific viral polymerases.
• Labeled Compound Synthesis: Acts as a starting material for the preparation of isotopically labeled (e.g., C13, N15) analogs for metabolic tracing studies.
• High-Throughput Screening (HTS): Utilized in compound libraries for screening against a variety of biological targets to identify new lead molecules.

Basic Information

Product Name	4-Oh-E1-1-N3Ade
CAS No.	488841-24-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	4-Hydroxy-E1-1-N3-adenine; 4-OH-E1-1-N3-Ade; 4-Hydroxy-1-N3-adenine derivative; 1-N3-Adenine, 4-hydroxy-E1- derivative; 4-Hydroxy-1,3-dideazaadenine analog; 4-OH-1,3-dideazapurine; Research compound 488841-24-3; Nucleoside analog intermediate 488841-24-3
EINECS	Contact for details

Quality Control

Our 4-Oh-E1-1-N3Ade is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our analytical methods, including HPLC and NMR, are validated to provide reliable specifications for our clients' critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider desiccants or an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.