Description

Elesclomol is a potent, small-molecule inducer of oxidative stress and apoptosis in cancer cells. This compound matters for its targeted mechanism of action, which exploits the altered metabolic state of malignant cells, making it a valuable tool in oncological research and development. It is primarily needed by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on developing novel cancer therapeutics and studying mitochondrial function and oxidative stress pathways. Elesclomol CAS NO 488832-69-5 represents a critical research chemical for advancing precision medicine in oncology.

Application

• Oncology Research: A key investigational agent for studying apoptosis and oxidative stress mechanisms in various cancer cell lines.
• Drug Discovery & Development: Used as a reference standard and active pharmaceutical ingredient (API) in preclinical studies for novel anti-cancer therapies.
• Biochemical Assays: Employed in high-throughput screening and in vitro assays to identify synergistic drug combinations or resistance mechanisms.
• Mitochondrial Function Studies: A critical tool for researching mitochondrial metabolism, reactive oxygen species (ROS) generation, and energy homeostasis.
• Academic & Institutional Research: Utilized in universities and research institutes for fundamental studies in cell biology and cancer pathology.
• Pharmacology Studies: Applied in pharmacokinetic (PK) and pharmacodynamic (PD) modeling to understand compound behavior in biological systems.

Basic Information

Product Name	Elesclomol
CAS No.	488832-69-5
Molecular Formula	C19H20N4O2S2
Molecular Weight	400.52 g/mol
Synonyms	STA-4783; (2E)-2-Pyridin-2-ylmethylene-N-[4-[(2,4,6-trimethylphenyl)sulfamoyl]phenyl]hydrazinecarbothioamide; Elesclomol sodium; Elesclomol (STA-4783); N'1-(4-((2,4,6-Trimethylphenyl)sulfamoyl)phenyl)-2-(pyridin-2-ylmethylene)hydrazine-1-carbothioamide
EINECS	Contact for details

Quality Control

Our Elesclomol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, identity confirmation via IR and MS, and residual solvent analysis, to ensure it meets high-purity standards suitable for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a desiccated environment. For long-term storage, consider conditions under an inert atmosphere to prevent oxidation.

Specification

Item	Specification
Appearance	Yellow to orange solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.