Description

2H-1,2,3-Triazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)-, Methyl Ester (9Ci) is a high-purity, multifunctional chemical building block essential for advanced organic synthesis. Its reactive chlorocarbonyl and ester groups make it a versatile intermediate for constructing complex heterocyclic scaffolds and active pharmaceutical ingredients (APIs). This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for lead optimization and novel compound library generation.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of triazole-containing drug candidates, including potential antivirals, antifungals, and kinase inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators that incorporate the triazole moiety.
• Peptide Mimetics & Conjugation: Serves as a reactive handle for peptide coupling and bioconjugation strategies due to its activated carbonyl group.
• Material Science Research: Intermediate in the development of functional polymers, metal-organic frameworks (MOFs), and ligands for catalysis.
• Chemical Biology Probes: Utilized to create tagged or labeled molecules for studying biological pathways and target engagement.

Basic Information

Product Name	2H-1,2,3-Triazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)-, Methyl Ester (9Ci)
CAS No.	488816-89-3
Molecular Formula	C5H4ClN3O3
Molecular Weight	189.56 g/mol
Synonyms	Methyl 5-(chlorocarbonyl)-2H-1,2,3-triazole-4-carboxylate; 5-(Chlorocarbonyl)-2H-1,2,3-triazole-4-carboxylic acid methyl ester; 1H-1,2,3-Triazole-4-carboxylic acid, 5-(chlorocarbonyl)-, methyl ester; Methyl 1H-1,2,3-triazole-4-carboxylate-5-carbonyl chloride; 488816-89-3; 2H-1,2,3-Triazole-4-carbonyl chloride, 5-methoxycarbonyl-
EINECS	Contact for details

Quality Control

Our 2H-1,2,3-Triazole-4-Carboxylic Acid, 5-(Chlorocarbonyl)-, Methyl Ester (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A Certificate of Analysis (COA) detailing all specifications is available with every shipment and upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.