Description

(4-Bromo-2,5-Difluorophenyl)Methanol is a versatile fluorinated and brominated benzyl alcohol derivative, serving as a critical building block in advanced organic synthesis. Its unique halogenated aromatic structure makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging the fluorine and bromine atoms for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modification: Acts as a functional monomer or cross-linking agent for introducing halogenated aromatic groups into specialty polymers.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new coupling reactions and constructing complex heterocyclic systems.
• Ligand & Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis, benefiting from the electron-withdrawing halogen substituents.

Basic Information

Product Name	(4-Bromo-2,5-Difluorophenyl)Methanol
CAS No.	486460-26-8
Molecular Formula	C7H5BrF2O
Molecular Weight	223.02 g/mol
Synonyms	(4-Bromo-2,5-difluorophenyl)methanol; 4-Bromo-2,5-difluorobenzyl alcohol; 2,5-Difluoro-4-bromobenzyl alcohol; (4-Bromo-2,5-difluorophenyl)carbinol; α-Hydroxymethyl-4-bromo-2,5-difluorobenzene; Benzenemethanol, 4-bromo-2,5-difluoro-; 4-Bromo-2,5-difluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Our production of (4-Bromo-2,5-Difluorophenyl)Methanol adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support cGMP standards for pharmaceutical applications and can tailor purity grades to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Standard Grade)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Single Impurity (HPLC)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.