Description

Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 4,7,7-Trimethyl-3-Oxo-, (1R,4S)- (9Ci) is a high-purity, stereochemically defined chiral building block. This compound is valued for its rigid bicyclic framework and reactive acid chloride functionality, making it an essential intermediate for the synthesis of complex molecules. It is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with specific three-dimensional structures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural complexity can contribute to unique biological activity and selectivity.
• Advanced Material Research: Serves as a precursor for specialty polymers and liquid crystals, leveraging its rigid, functionalized core to influence material properties.
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral catalysts and ligands for asymmetric synthesis, enhancing enantioselectivity in critical bond-forming reactions.
• Chemical Biology Probes: Utilized to create labeled compounds or molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 4,7,7-Trimethyl-3-Oxo-, (1R,4S)- (9Ci)
CAS No.	486402-86-2
Molecular Formula	C11H15ClO2
Molecular Weight	214.69 g/mol
Synonyms	(1R,4S)-4,7,7-Trimethyl-3-oxobicyclo[2.2.1]heptane-1-carbonyl chloride; (1R,4S)-Camphor-1-carbonyl chloride; (1R,4S)-1-Chlorocarbonyl-4,7,7-trimethyl-3-oxobicyclo[2.2.1]heptane; (1R,4S)-3-Oxo-4,7,7-trimethylbicyclo[2.2.1]heptane-1-carbonyl chloride; (1R,4S)-Camphoric acid chloride derivative; (1R,4S)-1-Carboxy-4,7,7-trimethyl-3-oxobicyclo[2.2.1]heptane chloride
EINECS	Contact for details

Quality Control

Our production of Bicyclo[2.2.1]Heptane-1-Carbonyl Chloride, 4,7,7-Trimethyl-3-Oxo-, (1R,4S)- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and enantiomeric excess. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.