Description

4'-C-Azidoadenosine CAS NO 478182-33-1 is a chemically modified nucleoside analog featuring an azido group at the 4'-carbon position of the ribose sugar. This unique structure makes it a valuable intermediate and building block for advanced biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the fields of medicinal chemistry, oligonucleotide synthesis, and the development of novel antiviral and anticancer agents.

Application

• Medicinal Chemistry Research: Serves as a key intermediate in the synthesis of novel nucleoside-based drug candidates for antiviral and anticancer therapies.
• Oligonucleotide Synthesis: Used as a modified building block for incorporating specific functionalities into oligonucleotides for diagnostic and therapeutic applications.
• Click Chemistry: The azido group enables efficient conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) for bioconjugation and probe labeling.
• Biochemical Probe Development: Acts as a precursor for creating photoaffinity labels or metabolic probes to study enzyme mechanisms and nucleic acid interactions.
• Academic & Industrial R&D: Employed in research laboratories for exploring new chemical biology tools and synthetic pathways.
• Pharmaceutical Intermediates: Functions as a critical synthetic intermediate in the production of more complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4'-C-Azidoadenosine
CAS No.	478182-33-1
Molecular Formula	C11H13N9O4
Molecular Weight	335.28 g/mol
Synonyms	4'-Azidoadenosine; 4'-C-Azido-adenosine; 9-[(2R,3R,4R,5R)-5-Azido-3,4-dihydroxyoxolan-2-yl]purin-6-amine; Adenosine, 4'-azido-; 4'-Azido-adenosine; 4'-Azido-A; 4'-N3-Adenosine
EINECS	Contact for details

Quality Control

Our 4'-C-Azidoadenosine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.