Description

4'-Azidocytidine is a chemically modified nucleoside analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and a versatile chemical probe for studying RNA biology and developing novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in nucleoside chemistry, antiviral drug discovery, and the development of mRNA-based technologies. The product is supplied with a focus on high purity and batch-to-batch consistency to meet the stringent demands of scientific investigation.

Application

• Biochemical Research Probe: Used as a key reagent for studying RNA structure, function, and metabolism through click chemistry and photoaffinity labeling techniques.
• Antiviral Drug Development: Investigated as a potential precursor or active pharmaceutical ingredient (API) in the synthesis of novel nucleoside analogs targeting viral polymerases.
• mRNA Technology & Vaccine Research: Employed in exploratory studies for the site-specific modification of mRNA to alter stability, translation efficiency, or immunogenicity.
• Nucleoside Chemistry & Synthesis: Serves as a specialized intermediate for organic chemists synthesizing novel modified nucleosides and nucleotides for various applications.
• Photocrosslinking Studies: The azido group enables UV-induced crosslinking, making it valuable for mapping RNA-protein interactions and other biomolecular complexes.

Basic Information

Product Name	4'-Azidocytidine
CAS No.	478182-28-4
Molecular Formula	C9H12N6O5
Molecular Weight	284.23 g/mol
Synonyms	4'-Azido-cytidine; 1-(4-Azido-4-deoxy-β-D-ribofuranosyl)cytosine; 4-Azidocytidine; 4'-N3-Cytidine; Cytidine, 4'-azido-; 4'-Azido-4-deoxycytidine
EINECS	Contact for details

Quality Control

Our 4'-Azidocytidine is manufactured under controlled conditions to ensure high chemical purity and stability. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to guarantee compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.