Description

(2-Fluoro-6-Methylphenyl)Methanol, also known as (6-Fluoro-o-Tolyl)Methanol, is a versatile fluorinated benzyl alcohol derivative that serves as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the strategic introduction of both fluorine and a hydroxymethyl group onto an aromatic ring, enabling precise modulation of molecular properties for high-value applications. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the fluorine atom improves lipophilicity and biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Employed in the synthesis of specialty monomers for advanced polymers and liquid crystals.
• Chemical Research & Development: A valuable scaffold for medicinal chemistry and structure-activity relationship (SAR) studies in academic and industrial labs.
• Fluorine Chemistry Building Block: Integral for introducing the fluorinated tolyl moiety into more complex molecular architectures.

Basic Information

Product Name	(2-Fluoro-6-Methylphenyl)Methanol / (6-Fluoro-o-Tolyl)Methanol
CAS No.	478163-35-8
Molecular Formula	C8H9FO
Molecular Weight	140.16 g/mol
Synonyms	(6-Fluoro-2-methylphenyl)methanol; 2-Fluoro-6-methylbenzyl alcohol; 1-(6-Fluoro-2-methylphenyl)methanol; (2-Fluoro-6-methylbenzyl) alcohol; 6-Fluoro-o-tolylmethanol; α-Hydroxymethyl-2-fluoro-6-methylbenzene; 2-(Hydroxymethyl)-3-fluorotoluene
EINECS	Contact for details

Quality Control

Our (2-Fluoro-6-Methylphenyl)Methanol is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flames. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.