Description

2,3-Dihydrothieno[3,4-B][1,4]Dioxin-5-Carbonyl Chloride is a high-value, reactive organic intermediate characterized by its fused heterocyclic dioxin-thiophene structure and an acid chloride functional group. This compound is a critical building block in advanced organic synthesis, enabling the precise introduction of complex heterocyclic motifs into target molecules. It is primarily sought after by research institutions and industrial R&D departments focused on developing novel materials and pharmaceuticals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Conductive Polymer Synthesis: Serves as a monomer or co-monomer for creating advanced polymers like PEDOT (poly(3,4-ethylenedioxythiophene)) analogs, used in organic electronics.
• Organic Semiconductor Development: Building block for small-molecule and polymeric semiconductors used in OLEDs, OFETs, and photovoltaic cells.
• Ligand and Catalyst Design: Used to synthesize sophisticated ligands for catalysis or metal-organic frameworks (MOFs).
• Agrochemical Research: Intermediate in the development of new-generation herbicides and fungicides with specific activity profiles.
• Dye and Pigment Chemistry: Precursor for functional dyes and pigments with specific electronic or optical properties.
• Academic & Industrial R&D: A versatile tool for synthetic chemists exploring new chemical spaces and reaction methodologies.

Basic Information

Product Name	2,3-Dihydrothieno[3,4-B][1,4]Dioxin-5-Carbonyl Chloride
CAS No.	477587-17-0
Molecular Formula	C7H5ClO3S
Molecular Weight	204.63 g/mol
Synonyms	2,3-Dihydrothieno[3,4-b][1,4]dioxine-5-carbonyl chloride; Thieno[3,4-b][1,4]dioxin-5-carbonyl chloride, 2,3-dihydro-; 2,3-Dihydrothieno[3,4-b]dioxine-5-carbonyl chloride; EDOT-COCl; 3,4-ethylenedioxythiophene-2-carbonyl chloride; PEDOT precursor acid chloride; 5-Carbonyl chloride-2,3-dihydrothieno[3,4-b][1,4]dioxin
EINECS	Contact for details

Quality Control

Our 2,3-Dihydrothieno[3,4-B][1,4]Dioxin-5-Carbonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, essential for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality systems support development under cGMP guidelines for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at temperatures between 2°C and 8°C (refrigerated). Due to its nature as a strong acid/organic solvent and reactive acid chloride, it must be kept under an inert atmosphere (e.g., nitrogen or argon) and separated from moisture, bases, and oxidizing agents. Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (THF, DCM, DMF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.